TGF-β antagonist attenuates fibrosis but not luminal narrowing in experimental tracheal stenosis
نویسندگان
چکیده
منابع مشابه
TGF-β antagonist attenuates fibrosis but not luminal narrowing in experimental tracheal stenosis.
OBJECTIVE Acquired tracheal stenosis (ATS) is an unusual disease often secondary to prolonged mechanical trauma. Acquired tracheal stenosis pathogenesis involves inflammation and subsequent fibrosis with narrowing of the tracheal lumen. Transforming growth factor-β1 (TGF-β) represents a pivotal factor in most fibrotic processes, and therefore a potential target in this context. The aim of this ...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 2016
ISSN: 0023-852X
DOI: 10.1002/lary.26402